Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Benfotiamine in Healthy Subjects

Lei Sheng,1,* Wei Cao,2,* Pingping Lin,3 Weili Chen,1 Hongrong Xu,1 Chunjiu Zhong,4 Fei Yuan,1 Hanjing Chen,1 Hui Li,1 Chao Liu,1 Mengjie Yang,1 Xuening Li1 1Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; 2Shanghai Rixin Biotechnology Co., Ltd, Shanghai, 200237, People&

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New early Pliocene owls from Langebaanweg, South Africa, with first evidence of Athene south of the Sahara and a new species of Tyto

The fossiliferous Upper Varswater Formation at Langebaanweg (South Africa) produced remains of at least five species of owls (Strigiformes).Tyto richae sp.nov.is the first palaeospecies of Tytonidae described Comb from an African fossil site, though indeterminate remains referable to the genus Tyto are known from the Middle Miocene of Morocco, the

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